2-[4-(Propan-2-yl)phenyl]cyclopropane-1-carboxylic Acid - Names and Identifiers
2-[4-(Propan-2-yl)phenyl]cyclopropane-1-carboxylic Acid - Physico-chemical Properties
| Molecular Formula | C13H16O2
|
| Molar Mass | 204.26 |
| Density | 1.136±0.06 g/cm3(Predicted) |
| Boling Point | 344.7±31.0 °C(Predicted) |
| pKa | 4.59±0.10(Predicted) |
2-[4-(Propan-2-yl)phenyl]cyclopropane-1-carboxylic Acid - Introduction
2-(4-Isopropyl-phenyl)-cycloprocyanecarboxylic acid is an organic compound with the chemical formula C15H18O2. The following are some properties, uses, preparation and safety information about the compound:
Nature:
-Appearance: Colorless or white crystal
-Melting Point: 77-80 ℃
-Boiling point: 335 ℃
-Density: 1.09g/cm³
Use:
2-(4-Isopropyl-phenyl)-cyclopropyleboxylic acid is commonly used in the field of organic synthesis, as a pharmaceutical and pesticide intermediates. It can be used to synthesize biologically active compounds and plays a key role in drug development and pesticide manufacturing.
Method:
2-(4-Isopropyl-phenyl)-cyclopanecarboxylic acid can be synthesized by the following steps:
1. Styrene was reacted with ethyl 2-bromopropionate in the presence of hydrochloric acid to obtain ethyl 2-(4-isopropylphenyl) acetate.
2. Reduction with cuprous chloride and phenol gives ethyl 2-(4-isopropylphenyl) cyclopropaneacetate.
3. Finally, ethyl 2-(4-isopropylphenyl) cyclopropaneacetate is hydrolyzed in the presence of a base to generate 2-(4-Isopropyl-phenyl)-cyclopropy1-phenyl)-cyclopropanecarboxylic acid.
Safety Information:
The specific safety of 2-(4-Isopropyl-phenyl)-cyclopanecarboxylic acid also needs to be evaluated according to specific circumstances. However, in general, it is necessary to follow laboratory safety procedures and wear appropriate personal protective equipment, such as laboratory gloves and goggles. Also, care needs to be taken to store and handle the compound to prevent it from coming into contact with the fire and oxidizing agents. When using or handling this compound, it is recommended to refer to the relevant safety data sheet (SDS) or consult a professional.
Last Update：2024-04-09 21:00:56